Heart Savior -™ is a proprietary blend of several well known ingredients that have been known for their cholesterol reducing characteristics and for overall heart health. After years of research by Doctors, this unique combination of ingredients has resulted in a revolutionary product that is an excellent non-prescription alternative for managing healthy cholesterol levels.
The ingredients used in Heart Savior ™ are always of the purest form available on the market today. There are many versions of these ingredients available, but Heart Savior only includes the precise levels for maximum results.
Recommended Use: As a dietary supplement, take two capsules in the morning and two capsules in the evening before meals.
Warning: Not intended for anyone under the age of 18. Do not use if you are pregnant, nursing, using statin drugs or other cholesterol lowering medications. Consult your physician if you are using any prescription medications or being treated for a pre-existing medical condition.
Supplement Facts:
Serving Size: 2 Capsules
Servings Per Container: 60
| |
Amount Per Serving |
% Daily Value |
| Selenium (as Seleno-L Methionine) |
100 mcg |
133% |
| Red Yeast Rice |
500 mg |
* |
| Phytosterol Esters |
400 mg |
* |
| Inositol Hexanicotinate |
50 mg |
* |
| Guggul Extracts providing 2.5% E&Z Guggulsterones |
50 mg |
* |
| Coenzyme Q10 |
30 mg |
* |
| Policosanol (from sugar cane) |
10 mg |
* |
Other Ingredients: Gelatin, Rice Flour, Magnesium Stearate, Soy.
Coenzyme Q10
Coenzyme Q10 (Co Q10) is produced by the human body and is necessary for basic cell function. Co Q10 functions as an antioxidant. Co Q10 is naturally present in small amounts in a variety of foods, but is particularly high in organ meats such as heart, liver and kidney, as well as beef, soy oil, sardines, mackerel, and peanuts. Co Q10 is synthesized in all tissues and a healthy individuals normal levels are maintained both by Co Q10 intake and by Co Q10 synthesis. It has no known toxicity or side effects.
Co Q10 levels decrease with age and are generally low in patients with certain chronic diseases including heart conditions, muscular dystrophies, Parkinson's disease, cancer, diabetes, and HIV/AIDS. Some prescription drugs can also lower Co Q10 levels. Levels of Co Q10 in the body can be increased by taking Co Q10 supplements.
Co Q10 levels decrease with age and are generally low in patients with certain chronic diseases including heart conditions, muscular dystrophies, Parkinson's disease, cancer, diabetes, and HIV/AIDS. Some prescription drugs can also lower Co Q10 levels. Levels of Co Q10 in the body can be increased by taking Co Q10 supplements.
Coenzyme Q10 and Heart Disease
Co Q10 is highly concentrated in heart muscle cells due to the high energy requirements of this cell type. Recent Co Q10 studies focus on heart disease, specifically, congestive heart failure which has been strongly correlated with significantly low blood and tissue levels of Co Q10. The severity of heart failure correlates with the severity of Co Q10 deficiency. This Co Q10 deficiency may cause heart muscle dysfunction.
What are CoQ10 Supplements
CoQ10 supplements are made from enzymes, amino acids, trace elements, and vitamins that encourage the body to create (biosynthesise) Coenzyme Q10. Every cell in the body has the ability to make Coenzyme Q10, but not all cells make the same amount. The muscles, heart, kidneys, liver, and pancreas are responsible for the bulk of your body's Coenzyme Q10 synthesis. The CoQ10 supplement in Heart Savior encourages this synthesis. Coenzyme Q10 biosynthesis is a long and complex series of biochemical reactions requiring a broad spectrum of vitamins, N-Acetyl Cysteine, other amino acids, and various trace elements. The benzoquinone portion of Coenzyme Q10 is synthesized from the amino acid tyrosine, while the isoprene side chain is synthesized from acetyl-CoA through the mevalonate pathway.
CoQ10 Research and Trials
Pioneering trials of Co Q10 in heart failure consisted primarily of patients with dilated weak heart muscle with unknown causes. Co Q10 was added to standard treatments for heart failure such as fluid pills, digitalis preparations, and ACE inhibitors. Several trials involved the comparison between supplemental Co Q10 and placebo on heart function as measured by echocardiography. Co Q10 was given orally in divided doses as a dry tablet chewed with a fat containing food or an oil based gel cap taken at mealtime. Heart function, as indicated by the fraction of blood pumped out of the heart with each beat, showed a gradual and sustained improvement in tempo with a gradual and sustained improvement in symptoms of fatigue, dyspnea, chest pain, and palpitations. The degree of improvement was occasionally dramatic with some patients developing a normal heart size and function on Co Q10 alone. Most of these dramatic cases were patients who began Co Q10 shortly after the onset of congestive heart failure. Patients with more established disease frequently showed clear improvement, but not a return to normal heart size and function.
There have been at least nine placebo controlled studies on the treatment of heart disease with Co Q10: two in Japan, two in the United States, two in Italy, two in Germany, and one in Sweden. All nine of these studies confirm the effectiveness of Co Q10 as well as its remarkable safety. There have now been eight international symposia on the biomedical and clinical aspects of Co Q10 (from 1976 through 1993). These eight symposia included over 300 papers presented by approximately 200 different physicians and scientists from 18 different countries. The majority of these scientific papers were Japanese (34%), with American (26%), Italian (20%) and the remaining 20% from Sweden, Denmark, Germany, United Kingdom, Belgium, Australia, Austria, France, India, Korea, Netherlands, Poland, Switzerland, USSR, and Finland. The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions that treatment with Co Q10 significantly improved heart muscle function while producing no adverse side effects or negative drug interactions.
The efficacy and safety of Co Q10 in the treatment of congestive heart failure, whether related to primary cardiomyopathies or secondary forms of heart failure, appears to be well established. The largest study to date is the Italian multicenter trial, by Baggio et al., involving 2664 patients with heart failure.
Recent work in heart failure examines the effect of Co Q10 on diastolic dysfunction, one of the earliest identifiable signs of myocardial failure that is often found in mitral valve prolapse, hypertensive heart disease and certain fatigue syndromes. Diastolic dysfunction might be considered the common denominator and a basic cause of symptoms in these three diagnostic groups of disease. Diastole is the filling phase of the cardiac cycle. Diastolic function has a larger cellular energy requirement than the systolic contraction and, therefore, the process of diastolic relaxation is more highly energy dependent and more highly dependent on Co Q10. This means it takes more energy to fill the heart than to empty it. Diastolic dysfunction is a stiffening of the heart muscle that interferes with the heart's ability to function as an effective pump. It is seen early with many common cardiac disorders and is detectable by echocardiography. The stiffening can return towards normal with supplemental Co Q10.
Red Yeast Rice
Red Rice Yeast has been used in China for centuries as both a food and as a medicinal substance. It is made by fermenting a type of yeast called Monascus purpureus over red rice. In Chinese medicine, red yeast rice is used to promote blood circulation, soothe upset stomach, and invigorate the function of the spleen, a body organ that destroys old blood cells and filters foreign substances.
In Asia, red yeast rice is a dietary staple and is used to make rice wine, as a flavoring agent and to preserve the flavor and color of fish and meat.
Red Yeast Rice forms naturally occurring HMG-CoA reductase inhibitors known as monacolins. The medicinal properties of red yeast rice favorably impact lipid profiles of people with high cholesterol (hypercholesterolemic patients).
Red Yeast Rice contains a family of nine different monacolins, all of which have the ability to inhibit HMG-CoA reductase which inhibits the production of cholesterol. Other active ingredients in red yeast rice include sterols, isoflavones, and monounsaturated fatty acids.
In a study conducted at UCLA School of Medicine, by David Heber, 83 people with high cholesterol levels received red yeast rice over a 12-week period. The study concluded that red yeast rice significantly reduces total cholesterol, LDL cholesterol, and total triglyceride concentrations when compared to those who received a placebo.
In a study involving 187 patients with elevated cholesterol were treated with red yeast rice daily for eight weeks. At the end of this eight-week trial, total cholesterol decreased by 16%, LDL by 21%, triglycerides by 24%. HDL cholesterol also increased by 14%.
In another 8-week trial involving a 324 people with high cholesterol levels, those who received red yeast rice experienced a significant drop in cholesterol levels compared to those who received placebo. Total cholesterol fell by 22.7%, LDL by 31%, and triglycerides by 34% in the red yeast rice group. HDL cholesterol increased by 20% in the red yeast rice group as well.
Not all Red Yeast Rice is the same and the source of the ingredient needs to be analyzed for purity of content. Heart Savior™ has the purest form available. Heart Savior addresses heart health and cholesterol levels much more comprehensively and effectively than red yeast rice alone.
Red Yeast Rice alone is good for fighting high cholesterol, but Heart Savior is a GREAT combination for lowering cholesterol and improving overall heart health.
Policosanol
Policosanol belongs to a family of wax-like phytochemicals prevalent throughout nature. This substance is used in the dietary supplement industry sourced from several foods that include: sugar cane, rice bran, beeswax, broccoli, spinach, alfalfa and oats.
Sugar cane derived policosanol is a new face on the cholesterol scene in the United States but is a popular hypocholesterolemic in other countries. The main policosanol form in sugar cane is octacosanol, a long-chain fatty alcohol found in the waxy film that covers the leaves and fruit of the plants that contain it.
Policosanol is a hypocholesterolemic compound that protects LDL cholesterol against oxidation, inhibits thromboxane, discourages blood clot formation, inhibits platelet aggregation, and increases exercise tolerance. Policosanol, at clinically evaluated dosages, has shown cholesterol-lowering properties comparable to low to medium dosage levels of the statins. According to several studies, policosanol has also shown antiplatelet effects, it prevents lipoprotein peroxidation, and beneficially affects atherosclerosis development. It has good tolerability and a low rate of clinical and laboratory adverse effects.
Policosanol is an effective alternative to lowering cholesterol for many people. In a study, 20 mg a day (over a 6- to 12-week period) resulted in the following lipid improvements: LDL cholesterol reduced about 28%, total cholesterol about 20%, and HDL increased by 7-10%. Triglycerides were unaffected. During the course of the trial, participants continued on a low cholesterol diet. In other studies policosanol was shown to lower triglycerides as well as lowering total and LDL cholesterol and raising HDL cholesterol.
Niacin
Large doses of niacin (as nicotinic acid, but not the niacinamide form) are prescribed to combat high blood pressure and to broadly improve blood cholesterol levels. Niacin is used to treat high Cholesterol because of its unique ability to improve lipid profiles for ApoB, LDL, small dense LDL, HDL, HDL2b - an extremely good cholesterol, Lp(a), fibrinogen and trigycerides. Pharmacologic doses of niacin (1.5 to 6 grams/day in divided doses) typically reduce LDL cholesterol levels by 10 to 25 percent and triglyceride levels by 20 to 50 percent. HDL cholesterol levels are also typically increased by 15 to 35 percent. An esterified, no-flush derivative of niacin called Inositol hexanicotinate (IHN), is slowly hydrolyzed and has no reported side effects using 4 grams daily. Peak blood concentrations have been reported to be at 10 hours, but suggested dosing is at least 4 times a day. It is used extensively in Europe for Raynaud's disease. There is no known monotherapeutic treatment for high cholesterol that is more broadly effective and as gentle.
Inositol Hexanicotinate ("Flush Free Niacin")
Flush-free niacin may lower cholesterol while boosting the beneficial HDL fraction. In a report on the antiatherogenic role of HDL (high density lipoprotein) cholesterol, flush-free niacin (inositol hexanicotinate) "appears to have the greatest potential to increase HDL cholesterol [by] 30%." This study was made over a 5-year period and focused on the effect of high LDL numbers exhibited before a patient's first coronary event(s). As reported in a November 1998 American Journal of Cardiology research study, "Nicotinic acid (niacin) has been shown to decrease triglyceride, increase HDL cholesterol, lower LDL cholesterol, and decrease lipoprotein (a); it also decreases fibrinogen," an additional benefit that reduces the risk of related cardiovascular disease.
Niacin in Heart Savior
Heart Savior combines the power of niacin with 6 other active ingredients in a breakthrough formula to lower cholesterol levels. The niacin used in Heart Savior, known as "flush free" niacin, allows your body's enzymes to gradually release the niacin over time to avoid the flushing response often associated with niacin and niacin side effects.
Selenium
Selenium is an essential trace mineral and is of fundamental importance to human health.
Selenium is one of the constituents of selenoproteins and has structural and enzymic roles. Selenium is best-known for its antioxidant properties and a catalyst for the production of active thyroid hormone.
Selenium is required for the proper performance of the immune system, and is believed to be a key nutrient in counteracting the development of virulence and inhibiting HIV progressing to AIDS.
Selenium is necessary for sperm motility and is believed to reduce the risk of miscarriage.
Selenium deficiency has also been linked to adverse mood states.
The links between selenium deficiency and heart disease remain inconclusive, however, there are links between oxidative stress and inflammation showing the benefits of higher selenium levels.
Higher selenium intake may be associated with reduced cancer risk. Large clinical trials are now planned to confirm or refute this hypothesis.
Low or diminishing selenium levels in some parts of the world, notably in some European countries, is a concern.
Selenium prevents ventricular tachycardia, is a hypolipidemic, and improves diabetic symptoms, congestive heart failure, and cardiomyopathy.
Cardiomyopathy is any disease that affects the structure and function of the heart. For example, the heart may become disabled as fibrous tissue partially replaces the heart muscle. The fibrous tissue degrades the heart's performance and the blood no longer moves efficiently.
The World Health Organization recognizes cardiomyopathy as a selenium deficiency. French researchers showed that chronic heart failure (associated with oxidative stress) appears to be relieved by selenium supplementation.
An excellent source of selenium is from clinically proven Heart Savior combining Selenium with 6 other extensively researched cholesterol fighting ingredients.
Guggulipid
This natural ingredient is derived from the mixture of plant chemicals (ketonic steroids) from the gum resin of Commiphora mukul, called guggulipid, and is an approved treatment of hyperlipidemia in India. It has been a mainstay of traditional Indian herbal medicine (Ayurveda) approaches in preventing high cholesterol and atherosclerosis. Clinical studies indicate it to be effective in the treatment of elevated cholesterol, elevated triglyceride levels and elevated LDL (bad cholesterol) levels. Studies have also shown that LDL oxidation, which is the main cause of plaque build in the arteries, can be prevented or at least decreased by the antioxidant activity of Guggul. Clinical studies on Guggul indicate that its hypolipidemic activity (decreasing cholesterol and other lipids) can be attributed to more than one mechanism. Three of the possible mechanisms include inhibition of cholesterol biosynthesis, e nhancing the rate of excretion of cholesterol and p romoting rapid degradation of cholesterol.
Guggul is typically manufactured in a standardized form that provides a fixed amount of guggulipid, the presumed active ingredients in Guggul. Guggul helps reduce high cholesterol because it lowers harmful LDL (low-density lipoproteins) while elevating the beneficial HDL (high-density lipoproteins). Guggul also has anti-inflammatory activity and reduces the levels of C-reactive proteins. It helps prevent blood platelet aggregation and breaks up blood clots. Thusly, Guggul can be used not only to lower bad cholesterol, but can be used as a preventative against heart disease and stroke.
Plant Sterols and Plant Stanols
Plant sterols and stanols represent a group of compounds that are an essential constituent of cell membranes in animals and plants. Cholesterol is actually a sterol of human cells, whereas phytosterols are produced by plants.
The most common plant sterols are sitosterol, campesterol, and stigmasterol. Plant sterols, although structurally similar to cholesterol, are not synthesized by the human body and are very poorly absorbed. The specific plant sterols that are currently incorporated into foods and supplements are extracted from soybean oil. The plant sterols, currently incorporated into foods, are esterified to unsaturated fatty acids (creating sterol esters) to increase lipid solubility, thus allowing maximal incorporation into a limited amount of fat. Some plant sterols currently available are saturated, to form the stanol derivatives, which are also effective at lowering cholesterol.
The plant sterols and stanols in Heart Savior ™ have been extensively studied and have proven not only to lower cholesterol but protect the heart as well. These plant chemicals are similar in structure to cholesterol. They have a slight chemical structure difference that, in comparison to cholesterol, are less absorbent. Plant sterols and stanols reduce cholesterol absorption by competing with cholesterol. You can think of it as "fake" cholesterol that dilutes your overall real cholesterol absorption and when less cholesterol is absorbed, less cholesterol returns to your liver lowering LDLs and overall cholesterol levels.
By lowering total and LDL cholesterol levels, plant sterols and stanols may also reduce your risk of heart disease. Studies have shown that taking plant sterols daily can lower cholesterol measurements by an average of 10% to 14%. The National Cholesterol Education Panel has suggested taking plant stanols and sterols along with a proper low fat diet and regular exercise program to help maintain normal cholesterol levels.
Heart Savior 
