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  Doctor's Best Collagen Types 1 & 3 (180 Tablets)
Doctor's Best Collagen Types 1 & 3 (180 Tablets )
Not Suitable For Vegetarians


 
Doctor's Best Science-Based Nutrition

180 Tablets
Suggested Use: Take (3) three tablets (2) two times daily on an empty stomach at least 30 minutes before meals. Do not mix with other protein powder supplements.
List Price: $21.99
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Description Ingredients
 

Best Collagen Types 1 & 3 (180 Tablets)

  • Science-Based Nutrition
  • Dietary supplement
  • Essential structural support for hair, skin, nails tendons, ligaments and bones*
Collagen is the major structural protein in connective tissue and the most abundant protein in the human body. It is responsible for maintaining the strength and flexibility of bones, joints, skin, tendons, ligaments, hair, nails, blood vessels and eyes, among other tissues throughout the body.

Best Collagen Types 1 & 3 contains pure collagen protein, providing the fundamental building blocks for growth and maintenance of healthy tissues.* Taken as a supplement, this product provides the body with the raw material needed to support the strength and integrity of essential structures.* Best Collagen Types 1 & 3 is enzymatically hydrolyzed into component amino acids with a low molecular weight for optimal absorption and utilization by the body.* Vitamin C is added to the formula, as it is an essential nutrient required for collagen synthesis by the body.*

There are a number of different types of collagen; the most prevalent two in the human body are types I and III. In fact, type I collagen is the most abundant protein in the human body—it is present in almost every type of tissue.1 Bone contains almost exclusively type I collagen. The collagen network in bone confers structural strength to bone tissue and prevents bone fragility. Deficient or defective collagen production, as can occur with aging, is a risk factor for fractures and other bone deformities.2

Type I collagen is also the major protein found in skin connective tissue where it is responsible for providing skin with its tensile strength and resiliency.3 Type III collagen is found at high levels in cardiovascular tissue and also in newly developing skin. It is essential for the proper development of the cardiovascular system and skin tissue. Types I and III collagen are often found together in the same tissues, as each form complements the structural integrity of the other.

Vitamin C is required for the synthesis of collagen and participates at nearly every step of the process. The critical role of vitamin C involves preventing the inactivation of several key enzymes required for collagen biosynthesis. Studies suggest that vitamin C enhances the function of fibroblasts and promotes an increased level of collagen deposition by these cells in human tissue.4 Vitamin C also functions to promote the strengthening of the collagen matrix and supports an increased level of collagen density in organs and tissues. These effects of vitamin C also suggest that intake levels of this vitamin may be inadequate as we age. As oxidative stress in tissues increases with age, there is an increased requirement for this crucial antioxidant vitamin to promote optimal collagen production.

Collagen and Normal Aging

Collagen synthesis is a continuous process throughout life. Collagen is essential for growth and repair, and is also produced during the process of wound healing. Rejuvenation and renewal of every tissue throughout the body requires the production of newly synthesized collagen. However, this process can become less efficient as we age, leading to decreased renewal of old tissue.5 This is manifested internally as a lessened efficiency of organ and tissue function. However, the most obvious manifestation of this process occurs externally. The most visible tissue in the body, and the most obvious place to observe the effects of aging, is the skin. As the skin ages, the levels of type I and III collagen, as well as elastin, decrease in the dermis, resulting in the loss of elasticity.3 This results in the appearance of wrinkles, fine lines and an aged look, as well as various skin blemishes and discoloration. The rate at which this occurs depends upon many factors including genetics, metabolic processes, hormonal changes and environmental exposures, such as to UV radiation from the sun or smoking tobacco (both of which can lead to increased break down of collagen in the skin and/or decreased synthesis of new collagen).6,7

Oxidative stress is thought to play a large role in the aging process as well. In general, while we are youthful, our body has the ability to combat the internal and external effects of oxidative stress more efficiently. However, as we age, and due to the genetic, metabolic and environmental changes mentioned above, often the amount of free radical production outpaces the antioxidant defenses of our body’s organs and tissues.

Since the body has become less efficient at dealing with the various stressors it encounters on a daily basis, it is even more critical to help it by providing the antioxidants and structural building blocks it needs to continually rejuvenate itself. Of course, a healthy diet that is rich in fruits and vegetables, as well as targeted nutritional supplementation, provide a wide range of antioxidants that the body can use to bolster its defense mechanisms. Furthermore, supplementing with Best Collagen can benefit the body by providing structural support.

Best Collagen contains the necessary building blocks for collagen renewal and the cofactors that enhance tissue strength and integrity. Replenishing the structural building blocks and antioxidants on a consistent basis can lead to healthy, vibrant and youthful tissue and organ function. Efficient collagen renewal also leads to strong, healthy bones. Outwardly, this manifests as supple skin with a decrease in wrinkles and blemishes, and an increase in strength and elasticity.

Scientific References

  1. Jensen LT, Høst NB. Collagen: scaffold for repair or execution. Cardiovasc Res. 1997 Mar;33(3):535-9.
  2. Vashishth D. The role of the collagen matrix in skeletal fragility. Curr Osteoporos Rep. 2007 Jun;5(2):62-6.
  3. Callaghan TM, Wilhelm KP. A review of ageing and an examination of clinical methods in the assessment of ageing skin. Part I: Cellular and molecular perspectives of skin ageing. Int J Cosmet Sci. 2008 Oct;30(5):313-22.
  4. Murad S, Grove D, Lindberg KA, Reynolds G, Sivarajah A, Pinnell SR. Regulation of collagen synthesis by ascorbic acid. Proc Natl Acad Sci U S A. 1981 May;78(5):2879-82.
  5. Sørensen LT. Effect of lifestyle, gender and age on collagen formation and degradation. Hernia. 2006 Dec;10(6):456-61.
  6. Chung JH, Seo JY, Choi HR, Lee MK, Youn CS, Rhie G, Cho KH, Kim KH, Park KC, Eun HC. Modulation of skin collagen metabolism in aged and photoaged human skin in vivo. J Invest Dermatol. 2001 Nov;117(5):1218-24.
  7. Yin L, Morita A, Tsuji T. Tobacco smoke extract induces age-related changes due to modulation of TGF-beta. Exp Dermatol. 2003;12 Suppl 2:51-6.

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All information on this site is provided for informational purposes only! By no means is any information presented herein intended to substitute for the advice provided to you by your own physician or health care provider. You should not use any information contained in our site to self-diagnose or personally treat any medical condition or disease or prescribe any medication. If you have or suspect you have a medical condition you are urged to contact your personal health care provider immediately. All health supplements or products purchased in this site contain clearly labeled product packaging, which must be read to ensure proper use. All information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

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